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Loss of Galectin-3 in the epidermis exacerbates psoriasis pathogenesis via inhibiting autophagy | Synapse
March 3, 2026
Loss of Galectin-3 in the epidermis exacerbates psoriasis pathogenesis via inhibiting autophagy
SH
Shanshan Han
MC
Meiqi Cheng
Hubei Polytechnic University
SJ
Shengtao Sheng Jiang
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Puntos clave
Loss of galectin-3 in the epidermis heightens psoriasis symptoms and severity.
Key evidence indicates significant inhibition of autophagy surrounding affected skin areas.
The method utilized included detailed analysis of epidermal cells in patients with psoriasis.
Highlighting the need for new treatment approaches targeting galectin-3 and autophagy pathways.
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Han et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75c38c6e9836116a24d75
https://doi.org/https://doi.org/10.1016/j.lfs.2026.124238
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