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Enantioselective CYP inhibition by diclofop, the active metabolite of diclofop-methyl: Mechanism and relevance for human exposure | Synapse
March 3, 2026
Enantioselective CYP inhibition by diclofop, the active metabolite of diclofop-methyl: Mechanism and relevance for human exposure
MB
Maike Felipe Santos Barbetta
GB
Giovanni Stoppa Baviera
LO
Leandro Oka-Duarte
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Puntos clave
CYP inhibition by diclofop shows significant enantioselectivity, highlighting its potential pharmacological effects.
The active metabolite of diclofop-methyl demonstrates distinct mechanisms affecting human health outcomes.
Observational analysis reveals critical interactions between diclofop and CYP enzymes relevant to human exposure.
Findings suggest that the relevance of enantioselective behavior warrants further safety evaluation regarding diclofop use.
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Cite This Study
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Barbetta et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75c54c6e9836116a25200
https://doi.org/https://doi.org/10.1016/j.toxlet.2026.111844