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Proliferation of activated hepatic stellate cells requires REST | Synapse
March 3, 2026
Open Access
Proliferation of activated hepatic stellate cells requires REST
VS
Vladimir S. Shavva
LT
Laura Tarnawski
WD
Wanmin Dai
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Puntos clave
Proliferation of hepatic stellate cells is influenced by REST activity, impacting liver fibrosis development.
Data shows that altering REST levels changes cell growth rates, demonstrating its crucial role in this process.
The method involved examining cellular behaviors in vitro, focusing on proliferation linked to REST expression.
Understanding the role of REST in stellate cells may lead to new strategies for treating liver fibrosis.
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Shavva et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75c7ac6e9836116a25659
https://doi.org/https://doi.org/10.1186/s10020-025-01406-z
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