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Dimeric triazole-chalcone conjugate as multi-target directed β-amyloid inhibitor | Synapse
March 3, 2026
Dimeric triazole-chalcone conjugate as multi-target directed β-amyloid inhibitor
SD
Shivani Daksh
Institute of Nuclear Medicine & Allied Sciences
SD
Shashank Deep
Indian Institute of Technology Delhi
AD
Anupama Datta
Institute of Nuclear Medicine & Allied Sciences
Puntos clave
The dimeric triazole-chalcone conjugate effectively inhibits β-amyloid formation, a key factor in neurodegeneration.
Significant inhibition of β-amyloid was observed with a maximum reduction of 75% in laboratory tests.
Observational analysis using in vitro models allowed us to assess the compound's multi-target capabilities against β-amyloid aggregation.
This research supports the need for further investigation of this inhibitor in clinical settings, with potential therapeutic implications.
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Cite This Study
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Daksh et al. (Wed,) studied this question.
synapsesocial.com/papers/69a75c84c6e9836116a2573d
https://doi.org/https://doi.org/10.1016/j.molliq.2026.129327