ADME profile of phencyclidine (PCP) analogues: emerging dissociative hallucinogens 3-MeO-PCP (CAS: 72242-03-6) and 4-MeO-PCP (CAS: 2201-35-6)—a multi-in silico approach for comprehensive prediction of absorption, distribution, metabolism and excretion relevant to clinical and forensic toxicology | Synapse
March 3, 2026
ADME profile of phencyclidine (PCP) analogues: emerging dissociative hallucinogens 3-MeO-PCP (CAS: 72242-03-6) and 4-MeO-PCP (CAS: 2201-35-6)—a multi-in silico approach for comprehensive prediction of absorption, distribution, metabolism and excretion relevant to clinical and forensic toxicology
Puntos clave
Dissociative hallucinogens like 3-MeO-PCP and 4-MeO-PCP show distinct pharmacokinetic profiles.
Comprehensive predictive modeling revealed important insights into their absorption and metabolism.
Analysis involves multi-in silico approaches across various physiological systems.
Potential implications for clinical and forensic toxicology highlight the need for further exploration.