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March 3, 2026
Open Access
Deciphering the regulatory landscape of enhancer RNAs in health and disease
QW
Qian Wang
Ministry of Education of the People's Republic of China
DD
Dirk Drasdo
Centre National de la Recherche Scientifique
CF
Chuannan Fan
Puntos clave
Enhancer RNAs play a crucial role in gene regulation, affecting various biological processes and conditions.
Key evidence indicates that most gene regulatory elements are also active as enhancer RNAs, which enhances gene expression.
This analysis utilizes molecular pathways to investigate the influence of transcription factors on enhancer RNAs in different contexts.
Understanding enhancer RNAs may enable new therapeutic strategies in treating diseases related to gene regulation dynamics.
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Wang et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75cd5c6e9836116a26065
https://doi.org/https://doi.org/10.1038/s41392-025-02436-z
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Deciphering the regulatory landscape of enhancer RNAs in health and disease | Synapse