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March 3, 2026
Open Access
SARS-CoV-2 nucleocapsid protein forms complexes with soluble complement regulatory proteins that can bind to the virion
JV
Jakub Víglaský
University of Veterinary Medicine in Košice
KB
Katarína Bhide
University of Veterinary Medicine in Košice
LT
Lea Talpašová
University of Veterinary Medicine in Košice
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Puntos clave
Nucleocapsid protein interacts with soluble complement regulatory proteins, enhancing virion stability.
This complex formation may help SARS-CoV-2 evade host immune responses, impacting infection outcomes.
Assessment of protein interactions indicates significant binding affinity, contributing to virion integrity.
Understanding these interactions emphasizes the need for targeted therapies against COVID-19.
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SARS-CoV-2 nucleocapsid protein forms complexes with soluble complement regulatory proteins that can bind to the virion | Synapse
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Víglaský et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75d15c6e9836116a268cc
https://doi.org/https://doi.org/10.1038/s41598-026-37866-4