Targeting the Nrf2/HO-1 aixs: A therapeutic strategy against regulated cell death in Alzheimer’s disease

Puntos clave

• Targeting the nrf2/ho-1 axis may reduce regulated cell death associated with alzheimer's disease, indicating therapeutic potential.
• Key evidence shows alterations in the nrf2 pathway and ho-1 levels align with oxidative stress measurements.
• Assessment using molecular and cellular assays reveals marked changes in regulated cell death pathways related to alzheimer's disease mechanisms.
• Findings suggest targeting this axis could lead to innovative therapies, highlighting the need for further exploration in clinical settings.