A highly efficient HA-targeted smart pH-responsive liposomal synergistic delivery system for TLR7/8 receptor agonist Imiquimod/methyl pyropheophorbide a-copper: Experimental study on remodeling the immune microenvironment of cold tumors and inhibiting tumor metastasis

Puntos clave

• Targeted delivery system remodels the immune microenvironment and inhibits tumor metastasis.
• Key findings include a significant reduction in metastasis rates in cold tumor models.
• Experimental study employs a liposomal delivery system with pH-responsive properties to improve drug efficacy.
• These findings may suggest new therapeutic strategies for enhancing immune response in tumor treatment.