Deep eutectic solvent-based ultrasonic-assisted extraction of polyphenols from Macadamia integrifolia green peel: COSMO-RS screening, process optimization, and its application in chitosan/polyvinyl alcohol films

Puntos clave

• Polyphenols were efficiently extracted from Macadamia integrifolia green peel using deep eutectic solvents.
• The extraction method achieved significant enhancement with ultrasonic-assisted techniques for improved yield.
• Optimization was guided by COSMO-RS screening to determine the most effective process parameters.
• Application in chitosan/polyvinyl alcohol films demonstrates potential for functional materials with increased antioxidant properties.