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A U-shaped association between vitamin D and ketone levels in type 2 diabetes: a metabolic state–dependent dual regulation mechanism | Synapse
March 3, 2026
Open Access
A U-shaped association between vitamin D and ketone levels in type 2 diabetes: a metabolic state–dependent dual regulation mechanism
XC
Xiang-Yu Chen
YZ
Yang Zhang
XW
Xiang-Xin Wang
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Puntos clave
Ketone levels are influenced by both high and low vitamin D levels, indicating a U-shaped relationship.
Participants with type 2 diabetes show varying ketone levels based on their vitamin D status, particularly at extremes.
This analysis examines metabolic regulation mechanisms affecting ketone levels in type 2 diabetes.
Findings highlight the importance of maintaining optimal vitamin D levels for better metabolic health.
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Chen et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75db9c6e9836116a27eef
https://doi.org/https://doi.org/10.1186/s13098-026-02101-7