Food-related adverse reactions in children may involve distinct immune mechanisms. Comprehensive interpretation of sIgE, sIgG, and sIgG4 profiles is recommended in the clinical assessment of pediatric allergic diseases. Among these biomarkers, sIgG and sIgG4 may provide additional reference values for management of food allergies, particularly when antigen exposure is chronic or long-term.
Shuangping Cai (Thu,) studied this question.