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Metabolic engineering and adaptive laboratory evolution enhance squalene production in Yarrowia lipolytica | Synapse
March 3, 2026
Open Access
Metabolic engineering and adaptive laboratory evolution enhance squalene production in Yarrowia lipolytica
QZ
Qiao-Qin Zhao
Hunan Agricultural University
PH
Peng-Cheng Hu
CZ
Chuan-Jiang Zhang
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Puntos clave
Squalene production was significantly enhanced, improving overall yield.
Key evidence shows a 50% increase in squalene levels after interventions.
Analysis involved metabolic engineering combined with adaptive laboratory evolution techniques.
This study highlights the potential for increased lipid biosynthesis in microbial systems for various applications.
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Zhao et al. (Fri,) studied this question.
synapsesocial.com/papers/69a75e78c6e9836116a2918e
https://doi.org/https://doi.org/10.1016/j.synbio.2026.01.017