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Age-dependent differences in airway inflammation and function in severe uncontrolled asthma | Synapse
March 3, 2026
Age-dependent differences in airway inflammation and function in severe uncontrolled asthma
JB
Jôse Mára de Brito
NC
Natália de Souza Xavier Costa
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
DF
Diogenes S. Ferreira
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
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Puntos clave
Airway inflammation is significantly different between age groups, impacting overall lung function.
In children, severe asthma shows higher levels of inflammation compared to adults, with implications for treatment strategies.
Observational analysis highlights the relationship between age and immune responses in severe uncontrolled asthma.
Findings suggest that age-specific approaches may enhance management and improve outcomes in asthma.
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Cite This Study
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Brito et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75e95c6e9836116a2954d
https://doi.org/https://doi.org/10.1016/j.jaci.2025.12.1015