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Metabolic crosstalk in the metastatic prostate cancer-bone microenvironment: mechanism, detection and therapeutic strategies | Synapse
March 3, 2026
Metabolic crosstalk in the metastatic prostate cancer-bone microenvironment: mechanism, detection and therapeutic strategies
RZ
Rui Zheng
YZ
Yingchao Zhao
LG
Luyao Gong
Ningbo No. 2 Hospital
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Puntos clave
Metabolic crosstalk significantly alters the bone microenvironment, impacting metastatic prostate cancer progression and therapy.
Key biomarkers related to this crosstalk were identified, providing potential targets for therapeutic strategies.
This observational analysis evaluates various detection methods to monitor metabolic changes in prostate cancer metastasis.
Findings may enhance treatment efficacy, though further studies will be needed to validate these strategies in clinical settings.
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Zheng et al. (Fri,) studied this question.
synapsesocial.com/papers/69a75e9bc6e9836116a2960f
https://doi.org/https://doi.org/10.1016/j.ejphar.2026.178611