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Targeting store-operated Ca2+ entry as a novel strategy to overcome treatment resistance in melanoma | Synapse
March 3, 2026
Targeting store-operated Ca2+ entry as a novel strategy to overcome treatment resistance in melanoma
DG
Daniela María Vega Gutiérrez
BN
Barbara A. Niemeyer
SK
Stephanie Kreis
University of Luxembourg
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Puntos clave
Treatment resistance in melanoma may be alleviated through the manipulation of store-operated calcium entry.
Key evidence indicates that targeting this calcium pathway can significantly enhance responsiveness to therapies.
Analysis employs a biochemical approach to understand calcium signaling mechanisms in melanoma cells.
Findings highlight the need for further exploration of calcium modulation strategies for effective melanoma therapies.
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Gutiérrez et al. (Sat,) studied this question.
synapsesocial.com/papers/69a75ee5c6e9836116a29e65
https://doi.org/https://doi.org/10.1016/j.bbcan.2026.189548