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Glucose deprivation drives LIF-dependent lung cancer | Synapse
March 3, 2026
Glucose deprivation drives LIF-dependent lung cancer
FL
Fedra Luciano-Mateo
JM
Joaquim Moreno-Caceres
MH
Miguel Hernández-Madrigal
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Puntos clave
Lung cancer cell growth is significantly enhanced under glucose deprivation, driven by LIF.
Cells exposed to glucose deprivation show increased proliferation rates, indicating a direct correlation with LIF levels.
Analysis identifies metabolic stress as a key factor influencing LIF-dependent pathways in lung cancer.
Findings may pave the way for new therapeutic strategies targeting glucose metabolism in lung cancer.
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Luciano-Mateo et al. (Fri,) studied this question.
synapsesocial.com/papers/69a75eebc6e9836116a29f02
https://doi.org/https://doi.org/10.1038/s42255-025-01437-0
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