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PINK1-associated Parkinson's disease: Motor and non-motor signs | Synapse
March 3, 2026
PINK1-associated Parkinson's disease: Motor and non-motor signs
AM
Anissa Azza Mousli
ZR
Zouari Rania
SZ
Saied Zakaria
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Puntos clave
PINK1-associated parkinson's disease presents distinct motor signs including bradykinesia and rigidity, impacting daily activities.
Non-motor signs such as depression and sleep disturbances are also significant, affecting overall quality of life.
Analysis of clinical data highlights a relationship between genetic mutations and symptom variability in Parkinson's disease.
Addressing both motor and non-motor symptoms may enhance management strategies and patient outcomes in PINK1-associated cases.
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Cite This Study
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Mousli et al. (Mon,) studied this question.
synapsesocial.com/papers/69a75eebc6e9836116a29f0a
https://doi.org/https://doi.org/10.1016/j.jns.2025.125290