Alveolar socket preservation (ASP) requires an ideal barrier membrane that provides anti-bacterial activity, water contact angle (WCA) and swelling behavior to support bone regeneration. This study evaluated these characteristics in a Polyvinyl Alcohol-Collagen-Hydroxyapatite composite membranes derived from the scales of Lates calcarifer.L. The PVA-Col-HA CM was produced from the scales of Lates calcarifer through mixing, homogenization, casting, and drying and then divided into three groups: non-irradiated, 15 kGy irradiation, and 25 kGy irradiation. Antibacterial activity was assessed by disk-diffusion test and inhibition zone diameters were measured. Water contact angle was determined using a contact angle goniometer on both membrane surfaces. Swelling behavior was evaluated by immersing samples in phosphate-buffered saline for 60 minutes, followed by periodic weighing and calculation using a swelling formula. The anti-bacterial activity test showed a larger zone of inhibition in the 25 kGy group by 2mm on Escherichia coli and Staphylococcus aureus. One-way ANOVA test of WCA values showed significant differences (p 0.05) among groups, but the linear graph shows that the 25kGy group displayed the lowest and most stable swelling profile. These findings suggest that the PVA-Col-HA CM exhibited favorable anti-bacterial activity, WCA, and swelling behavior, with optimal performance observed in the 25 kGy irradiation group.
Ariesanti et al. (Wed,) studied this question.