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Relationship between perturbation specificity and functional dispensability in yeast phosphoproteome | Synapse
March 3, 2026
Relationship between perturbation specificity and functional dispensability in yeast phosphoproteome
YH
Yilun Han
YX
Yu Xia
Puntos clave
Functional dispensability correlates with perturbation specificity in yeast phosphoproteome.
Results show a significant relation, with 70% of analyzed proteins demonstrating similar behavior under different conditions.
Observational analysis across several phosphoproteomic datasets highlights how perturbations affect cellular functions distinctly.
Understanding these relationships may enable the development of targeted interventions in yeast and other systems.
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Han et al. (Thu,) studied this question.
synapsesocial.com/papers/69a75f3ec6e9836116a2a794
https://doi.org/https://doi.org/10.1016/j.bpj.2026.01.055
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