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Galcanezumab-induced elevated calcitonin gene-related peptide level in episodic cluster headache | Synapse
March 3, 2026
Galcanezumab-induced elevated calcitonin gene-related peptide level in episodic cluster headache
HL
Hye Jeong Lee
Yonsei University
MC
Min Kyung Chu
JS
Jeong Soo Sung
Yonsei University
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Puntos clave
Elevated calcitonin gene-related peptide levels are associated with episodic cluster headache.
The specific mechanism of action of galcanezumab in this context remains unclear, but it indicates a potential pathway.
Analysis was performed on patients receiving galcanezumab for cluster headache management.
Further studies are warranted to explore these neuropeptide interactions in pain pathways.
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Lee et al. (Mon,) studied this question.
synapsesocial.com/papers/69a75f7cc6e9836116a2ae2e
https://doi.org/https://doi.org/10.1016/j.jns.2025.124691