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Multi-cohort and single-cell profiling of aging genes reveals prognostic and therapeutic targets in breast cancer | Synapse
March 3, 2026
Open Access
Multi-cohort and single-cell profiling of aging genes reveals prognostic and therapeutic targets in breast cancer
LH
Li Huang
LZ
Lei Zhang
University of Science and Technology of China
XS
Xiaoyu Shi
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Puntos clave
Breast cancer outcomes relate significantly to identified aging genes, with implications for therapy.
Aging genes serve as prognostic markers, impacting treatment plans and predictions for breast cancer progression.
Multi-cohort and single-cell profiling approaches elucidated the critical role of aging genes in tumor biology.
While findings are promising, external validation in broader cohorts is essential for clinical application.
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Huang et al. (Fri,) studied this question.
synapsesocial.com/papers/69a75f8fc6e9836116a2b045
https://doi.org/https://doi.org/10.1016/j.isci.2026.114847