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Reduced Dose Post Transplant Cyclophosphamide (PTCy) Is Associated with Improved Count Recovery without Significant Acute and Chronic GVHD | Synapse
March 3, 2026
Reduced Dose Post Transplant Cyclophosphamide (PTCy) Is Associated with Improved Count Recovery without Significant Acute and Chronic GVHD
SM
Shahram Mori
Sarah Cannon Research Institute
Puntos clave
Improved count recovery is observed with reduced dose of cyclophosphamide after transplant, indicating a potential benefit.
Count recovery rates in this cohort were notably higher, with no significant increase in acute or chronic GVHD.
Observational analysis recorded outcomes of transplant recipients receiving varied cyclophosphamide doses to assess recovery.
This study highlights the need for optimized dosing strategies to mitigate GVHD while promoting effective recovery.
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Shahram Mori (Sun,) studied this question.
synapsesocial.com/papers/69a76029c6e9836116a2ca22
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.412
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