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Effects of crocetin, a constituent of saffron, on indomethacin-induced gastric ulcer and related anxiety-like behavior in rats | Synapse
March 3, 2026
Effects of crocetin, a constituent of saffron, on indomethacin-induced gastric ulcer and related anxiety-like behavior in rats
ST
Sina Tamaddonfard
AF
Amir Abbas Farshid
ET
Esmaeal Tamaddonfard
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Puntos clave
Crocetin significantly reduces gastric ulcer severity, improving animal welfare.
In rats administered indomethacin, treated groups showed 50% less ulceration compared to controls.
Assessment using a rat model showed the behavioral effects alongside ulcer healing.
Findings imply that saffron compounds like crocetin may provide dual therapeutic effects.
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Tamaddonfard et al. (Tue,) studied this question.
synapsesocial.com/papers/69a76029c6e9836116a2ca45
https://doi.org/https://doi.org/10.1016/j.phymed.2026.157918
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