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March 3, 2026
m5c-modified LINC01094 participates in epithelial-mesenchymal transition and metastasis of cervical cancer cells via the ZNF582-SIRT1/p53 axis
XL
Xia Lu
LY
Lili Yao
Merck & Co., Inc., Rahway, NJ, USA (United States)
XX
Xu Xu
Nanjing Agricultural University
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Puntos clave
Epithelial-mesenchymal transition is significantly influenced by m5c-modified LINC01094, driving metastasis in cervical cancer cells.
Impact on the znf582-sirt1/p53 axis indicates a critical pathway in cancer progression, emphasizing its importance in cancer biology.
Assessment using cellular assays demonstrates changes in cancer cell behavior linked to LINC01094 modification and metabolic pathways.
Findings underline the potential for targeting the LINC01094 pathway in therapeutic strategies for cervical cancer.],
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Cite This Study
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Lu et al. (Tue,) studied this question.
synapsesocial.com/papers/69a76034c6e9836116a2cb53
https://doi.org/https://doi.org/10.1007/s00335-026-10200-z
m5c-modified LINC01094 participates in epithelial-mesenchymal transition and metastasis of cervical cancer cells via the ZNF582-SIRT1/p53 axis | Synapse