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Differential Gene Expression during Conditioning Correlates with Outcomes in Allotransplant Recipients with AML and MDS | Synapse
March 3, 2026
Differential Gene Expression during Conditioning Correlates with Outcomes in Allotransplant Recipients with AML and MDS
BG
Boglarka Gyurkocza
Memorial Sloan Kettering Cancer Center
IJ
Isaac Jenkins
Fred Hutch Cancer Center
BS
Bart L Scott
University of Washington
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Puntos clave
Outcomes in allotransplant recipients are influenced by differential gene expression observed during conditioning.
Gene expression changes correlate with patient outcomes, particularly in acute myeloid leukemia and myelodysplastic syndromes.
Analysis focuses on gene expression profiles during conditioning prior to allotransplant procedures across various cases.
Potential implications highlight new therapeutic approaches to improve transplant success and patient care.
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Gyurkocza et al. (Sun,) studied this question.
synapsesocial.com/papers/69a7604cc6e9836116a2ce59
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.085
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