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Delactylation of the tumor suppressor ARHGDIB drives metastasis and chemoresistance in bladder cancer | Synapse
March 3, 2026
Open Access
Delactylation of the tumor suppressor ARHGDIB drives metastasis and chemoresistance in bladder cancer
GX
Guanghui Xu
YL
Yuqin Li
University of British Columbia
SP
Shan Peng
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Puntos clave
Metastasis rates are significantly linked to ARHGDIB delactylation, promoting aggressive cancer behavior.
Delactylation of the tumor suppressor correlates with increased chemoresistance in bladder cancer cells.
This analysis utilizes cellular assays and molecular characterization methods to demonstrate critical pathways.
These findings highlight potential interventions targeting delactylation in bladder cancer to improve treatment outcomes.
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Xu et al. (Sun,) studied this question.
synapsesocial.com/papers/69a7604cc6e9836116a2ce64
https://doi.org/https://doi.org/10.1016/j.celrep.2026.116941
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