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Multi-Omic and Functional Characterization of Bone Marrow Regulatory T cells for Enhanced GVHD Prevention | Synapse
March 3, 2026
Multi-Omic and Functional Characterization of Bone Marrow Regulatory T cells for Enhanced GVHD Prevention
JD
Jessica Diarra
CB
Cameron S. Bader
DH
Daniel Ho
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Puntos clave
Graft versus host disease prevention shows improved outcomes with enhanced bone marrow regulatory T cells.
Key evidence demonstrates a 30% reduction in GVHD incidence through optimized T cell therapies.
Multi-omic analyses of bone marrow cells uncover critical immune pathways linked to T cell function.
Findings highlight the need for further clinical investigations to translate these insights into effective treatments.
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Diarra et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76055c6e9836116a2cf95
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.337
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