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Correction: GRB2 promotes brain metastasis in HER2-positive breast cancer by regulating the Ras/MAPK pathway | Synapse
March 3, 2026
Open Access
Correction: GRB2 promotes brain metastasis in HER2-positive breast cancer by regulating the Ras/MAPK pathway
HL
Hongyu Li
Kunming University of Science and Technology
YY
Yuan Yang
South China Normal University
XH
Xiao Han
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Puntos clave
Brain metastasis is significantly influenced by GRB2 activity, impacting treatment outcomes.
The Ras/MAPK pathway is a critical mediator in GRB2's modulation of metastasis.
Analysis of HER2-positive breast cancer cell lines revealed specific interactions involving GRB2.
Targeting GRB2 may offer new therapeutic strategies for managing advanced breast cancer.
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Li et al. (Tue,) studied this question.
synapsesocial.com/papers/69a76066c6e9836116a2d1c3
https://doi.org/https://doi.org/10.1038/s41598-026-37879-z
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