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High Incidence of Gvhd after Tapering Off Immunosuppression to Increase Donor T cell Chimerism | Synapse
March 3, 2026
High Incidence of Gvhd after Tapering Off Immunosuppression to Increase Donor T cell Chimerism
MS
Michael W Schuster
FL
Fengshuo Lan
Stony Brook University Hospital
BJ
Bita Jalilizeinali
Puntos clave
High incidence of graft-versus-host disease (Gvhd) follows tapering immunosuppression, posing risks.
Observational analysis shows that increased donor T cell chimerism correlates with Gvhd incidence.
This analysis evaluated immune responses in patients undergoing reduced immunosuppression protocols.
Highlighting the need for careful monitoring during immunosuppression tapering to prevent Gvhd.
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Schuster et al. (Sun,) studied this question.
synapsesocial.com/papers/69a76069c6e9836116a2d226
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.422
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