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Ceramides may Play a Central Role in the Pathogenesis of Alzheimer's Disease: a Review of Evidence and Horizons for Discovery | Synapse
March 3, 2026
Open Access
Ceramides may Play a Central Role in the Pathogenesis of Alzheimer's Disease: a Review of Evidence and Horizons for Discovery
HK
Hans O. Kalkman
University of Zurich
LS
Lukasz Smigielski
University of Zurich
Puntos clave
Ceramides may significantly influence the pathogenesis of Alzheimer's disease—affecting neuronal health.
Research indicates a link between ceramide levels and neuroinflammation, impacting disease progression.
Observational analysis of multiple studies suggests that ceramides act as crucial biomarkers for Alzheimer's disease.
Understanding how ceramides contribute to Alzheimer's may open up new therapeutic avenues for treatment.
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Kalkman et al. (Sat,) studied this question.
synapsesocial.com/papers/69a7608ec6e9836116a2d6ab
https://doi.org/https://doi.org/10.5167/uzh-284378
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