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Shadows after the Light: Persistent Cytopenia Post–CAR T-cell Therapy: | Synapse
March 3, 2026
Shadows after the Light: Persistent Cytopenia Post–CAR T-cell Therapy:
SS
Sundar Shewale
AB
Akash Bhojgaria
DG
Danish Ghazali
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Puntos clave
Persistent cytopenia occurs in a significant number of patients following CAR T-cell therapy, impacting recovery timelines.
At 6 months, 45% of patients exhibit ongoing cytopenia, highlighting the delayed immune recovery that challenges overall health.
Analysis of patient records reveals a correlation between initial response and subsequent bone marrow function post therapy.
Findings emphasize the importance of long-term hematologic monitoring, as late effects may influence clinical outcomes.
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Shewale et al. (Sun,) studied this question.
synapsesocial.com/papers/69a7608ec6e9836116a2d6ac
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.288
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