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Cord Blood Transplant with Abatacept and Low-Dose ATG for TP53-Mutated Complex Karyotype AML: A Single-Center Report | Synapse
March 3, 2026
Cord Blood Transplant with Abatacept and Low-Dose ATG for TP53-Mutated Complex Karyotype AML: A Single-Center Report
RY
Rachael Yasuda
ND
Nicolas DePadova
HP
Haley Pebler
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Puntos clave
Cord blood transplant with abatacept and low-dose ATG showed improved outcomes in TP53-mutated AML.
The combination treatment led to significant survival rates, with 80% of patients alive at one year.
Observational analysis at a single center included patients with complex karyotype AML, focusing on their response to the treatment.
Implications highlight the need for further studies to validate efficacy and explore long-term effects of the approach.
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Yasuda et al. (Sun,) studied this question.
synapsesocial.com/papers/69a7609bc6e9836116a2d864
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.587
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