Impact of HLA Alloimmunization on Availability of HLA Matched and Mismatched Unrelated Allogeneic Hematopoietic Cell Donors for Transplantation Disproportionately Impacts Female Patients | Synapse
March 3, 2026
Impact of HLA Alloimmunization on Availability of HLA Matched and Mismatched Unrelated Allogeneic Hematopoietic Cell Donors for Transplantation Disproportionately Impacts Female Patients
Puntos clave
HLA alloimmunization reduces the availability of matched unrelated donors, especially impacting female patients.
Among a diverse population, only a small percentage of female patients find compatible HLA matched donors.
Assessment of donor databases highlights trends in HLA matching rates across genders and populations.
The findings urge further exploration of strategies to enhance donor matching, especially for women.