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In the Post-Transplant Cyclophosphamide (PTCy) Era, Overall Survival (OS) By Donor Differs By Recipient and Donor Age and Race/Ethnicity | Synapse
March 3, 2026
In the Post-Transplant Cyclophosphamide (PTCy) Era, Overall Survival (OS) By Donor Differs By Recipient and Donor Age and Race/Ethnicity
MH
Megan Herr
NN
Nisha M. Nair
SH
Shernan G. Holtan
Roswell Park Comprehensive Cancer Center
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Overall survival is influenced by both donor and recipient characteristics, highlighting the complexity of transplant outcomes.
Key evidence indicates survival rates differ significantly based on donor age and race/ethnicity, emphasizing disparities in care.
Analysis of transplant outcomes demonstrates variations in survival linked to specific donor-recipient age pairings and ethnic backgrounds.
The findings call for careful consideration of donor characteristics in transplant protocols, as they likely affect patient outcomes.
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Herr et al. (Sun,) studied this question.
synapsesocial.com/papers/69a760c4c6e9836116a2dd2d
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.955
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