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CD6-CAR Tregs Safety and Early Evidence of Therapeutic Effect in Patients with Chronic Graft-Versus-Host Disease | Synapse
March 3, 2026
CD6-CAR Tregs Safety and Early Evidence of Therapeutic Effect in Patients with Chronic Graft-Versus-Host Disease
AS
Amandeep Salhotra
DY
Dongyun Yang
City of Hope
JW
Jamie R. Wagner
City Of Hope National Medical Center
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Puntos clave
CD6-CAR Tregs demonstrate early signs of therapeutic effect in chronic graft-versus-host disease.
Out of the assessed patients, a notable proportion experienced improved health metrics during treatment.
The analysis leverages immunotherapy approaches to target chronic graft-versus-host disease effectively.
The findings may encourage wider adoption of CD6-CAR Tregs but require further validation in larger cohorts.
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Salhotra et al. (Sun,) studied this question.
synapsesocial.com/papers/69a760dcc6e9836116a2e00b
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.212