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Liver-specific SLC13A3 modulation alleviates MASLD by regulating NAD+ metabolism | Synapse
March 3, 2026
Liver-specific SLC13A3 modulation alleviates MASLD by regulating NAD+ metabolism
JD
Jiangxia Du
Zhejiang Lab
MS
Miao Shen
YM
Yuan Mu
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Puntos clave
Alleviating MASLD is achievable through regulation of NAD+ metabolism, enhancing liver function.
Key evidence indicated a significant decrease in MASLD symptoms correlating with SLC13A3 modulation.
Analysis of liver tissue shows how specific modulation of SLC13A3 impacts NAD+ levels and metabolic activity.
This approach highlights a promising pathway for treating metabolic disorders related to liver health.
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Cite This Study
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Du et al. (Sat,) studied this question.
synapsesocial.com/papers/69a76112c6e9836116a2e9dc
https://doi.org/https://doi.org/10.1007/s11010-026-05501-5