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Diosgenin Attenuates Angiogenesis via Targeting Src/STAT3 Signaling Pathway to Treat Non-Small Cell Lung Cancer | Synapse
March 3, 2026
Diosgenin Attenuates Angiogenesis via Targeting Src/STAT3 Signaling Pathway to Treat Non-Small Cell Lung Cancer
WL
Wan-yu Li
YW
Yuhan Wang
QW
Qing-Ting Wang
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Puntos clave
Diosgenin significantly decreases angiogenesis in non-small cell lung cancer models, suggesting therapeutic potential.
Key evidence shows a 50% reduction in angiogenic activity after treatment with diosgenin in vitro.
Analysis of the src/stat3 signaling pathway reveals that diosgenin inhibits this pathway's activation effectively.
This study highlights a promising avenue for treating non-small cell lung cancer through targeting specific molecular pathways.
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Li et al. (Sat,) studied this question.
synapsesocial.com/papers/69a76114c6e9836116a2ea39
https://doi.org/https://doi.org/10.1007/s11655-026-4138-4
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