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LAV-BPIFB4 reverses progeria-associated cardiac aging by restoring diastolic function and reducing senescence | Synapse
March 3, 2026
Open Access
LAV-BPIFB4 reverses progeria-associated cardiac aging by restoring diastolic function and reducing senescence
UC
Unbin Chae
YP
Young‐Ho Park
Korea Research Institute of Standards and Science
TK
Taeho Kwon
Korea Research Institute of Bioscience and Biotechnology
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Puntos clave
LAV-BPIFB4 improves diastolic function, indicating enhanced heart performance in progeria.
The intervention may reduce senescence, an aging-related process detrimental to heart health.
Observational analysis reveals significant improvements in cardiac function over a designated study period.
This highlights potential new treatments for age-related heart issues in individuals with progeria.
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Chae et al. (Thu,) studied this question.
synapsesocial.com/papers/69a76147c6e9836116a2f0f2
https://doi.org/https://doi.org/10.7150/ijbs.129092
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