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A Comprehensive Study of AAV Tropism in the Marmoset Brain | Synapse
March 3, 2026
A Comprehensive Study of AAV Tropism in the Marmoset Brain
KF
Kailun Fang
HL
Hailin Liu
YY
Yuting Yao
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Puntos clave
AAV tropism varies significantly across different brain regions, impacting gene delivery efficiency.
Key metrics indicate that certain viral vectors achieve over 60% transduction rates in the marmoset cortex.
Analysis of neuroanatomy through advanced imaging techniques highlights targeted delivery potential.
Findings suggest optimized AAV vector designs could enhance gene therapy effectiveness for neurological conditions.
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Cite This Study
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Fang et al. (Tue,) studied this question.
synapsesocial.com/papers/69a761d3c6e9836116a2fe66
https://doi.org/https://doi.org/10.1007/s12264-026-01591-9