Metastasis-directed therapy and standard of care versus standard of care for oligometastatic prostate cancer (WOLVERINE): a systematic review and individual patient data meta-analysis from the X-MET collaboration | Synapse
March 3, 2026
Metastasis-directed therapy and standard of care versus standard of care for oligometastatic prostate cancer (WOLVERINE): a systematic review and individual patient data meta-analysis from the X-MET collaboration
Puntos clave
Improved outcomes are associated with metastasis-directed therapy in oligometastatic prostate cancer.
The systematic review analyzed individual patient data from the X-MET collaboration with 150 studies involved.
Observational analysis focused on the effectiveness of combining metastasis-directed therapy with standard care.
These findings may influence treatment guidelines, but further validation in diverse populations is needed.