Urinary thrombin as a non-invasive biomarker in renal diseases: a possible role in the detection of segmental sclerosis lesions in IgA nephropathy

Puntos clave

• Urinary thrombin levels are associated with segmental sclerosis in renal diseases, particularly IgA nephropathy.
• Elevated urinary thrombin levels were observed in patients with segmental sclerosis lesions, pointing to its potential as a biomarker.
• Observational analysis highlighted the role of urinary thrombin as a non-invasive marker for renal disease assessment.
• Findings suggest a new approach for diagnosing renal conditions, potentially reducing the need for invasive biopsy procedures.