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Bioactive galloylquinic acids from Copaifera lucens as dual inhibitors of SARS-CoV-2 Spike and RdRp proteins | Synapse
March 3, 2026
Open Access
Bioactive galloylquinic acids from Copaifera lucens as dual inhibitors of SARS-CoV-2 Spike and RdRp proteins
RE
Rasha M. El-Morsi
LA
Lamiaa A. Al-Madboly
Tanta University
JB
Jairo K. Bastos
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Puntos clave
Inhibition of both spike protein and RdRp proteins indicates bioactive potential of galloylquinic acids, enhancing their therapeutic relevance.
In vitro tests show that specific galloylquinic acids effectively reduce viral activity against SARS-CoV-2 with promising results.
Analysis of molecular binding suggests that these natural compounds can effectively target key viral proteins involved in replication.
The findings highlight the potential for developing new treatments based on plant-derived compounds, with further research needed.
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El-Morsi et al. (Mon,) studied this question.
synapsesocial.com/papers/69a765c7badf0bb9e87da669
https://doi.org/https://doi.org/10.1038/s41598-025-25217-8