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CAR Signaling Informs Mechanisms to Enhance Metabolism and Function in γδ T Cells | Synapse
March 3, 2026
Open Access
CAR Signaling Informs Mechanisms to Enhance Metabolism and Function in γδ T Cells
DA
Daniel Abate-Daga
Moffitt Cancer Center
XP
Xiomar Bustos Perez
LT
Leticia Tordesillas
Moffitt Cancer Center
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Puntos clave
Enhanced metabolism significantly improves γδ T cell function, supporting immune responses.
Key evidence shows increased glycolysis and cytokine production in activated γδ T cells.
Observational analysis examines CAR signaling pathways involved in γδ T cell activation and metabolism.
Findings suggest CAR signaling could enhance immunotherapy strategies, though further studies are needed.
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Abate-Daga et al. (Mon,) studied this question.
synapsesocial.com/papers/69a765e0badf0bb9e87dad0d
https://doi.org/https://doi.org/10.21203/rs.3.rs-8704178/v1