Comparative evaluation of practical in-vitro methods for testing synergy between ceftazidime-avibactam and aztreonam against metallo-β-lactamase and serine carbapenemase-producing Enterobacterales species

Puntos clave

• Significant synergy was observed with the combination of ceftazidime-avibactam and aztreonam.
• Using practical methods, such as disk replacement and inverse D-zone, proved effective.
• These methods are suitable for routine testing in resource-limited settings, enhancing treatment options.
• Highlighting the combination's effectiveness may lead to better management of antibiotic resistance.