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The moonlighting functions of glycolytic enzymes in tumorigenesis | Synapse
March 3, 2026
Open Access
The moonlighting functions of glycolytic enzymes in tumorigenesis
XC
Xin Jennifer Chen
Jiangsu Academy of Agricultural Sciences
JY
Jing Yang
Xuzhou Medical College
YM
Yongjun Ma
Jinhua Central Hospital
Puntos clave
Glycolytic enzymes play essential roles beyond energy production in cancer cells, impacting their growth dynamics.
Key findings indicate that these enzymes can act as oncogenes, driving tumorigenesis through metabolic reprogramming.
Analysis of experimental models demonstrates how glycolytic pathways promote cancer cell survival and proliferation.
The discovery highlights the potential for targeting metabolic pathways in cancer treatment strategies.
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Chen et al. (Mon,) studied this question.
synapsesocial.com/papers/69a76646badf0bb9e87dc647
https://doi.org/https://doi.org/10.1007/s13402-025-01135-9
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