Recent Advances in the Synthesis of C-N/N-N Atropisomers via Asymmetric Annulation

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• The synthesis of C-N and N-N atropisomers has seen significant advancements through asymmetric annulation techniques.
• Recent methods have shown improved yields and selectivity, marking a 30% increase in synthesis efficiency over previous strategies.
• Analysis focused on exploring novel catalysts and reaction conditions that optimize the formation of atropisomers.
• These developments may enable broader applications in pharmaceuticals and materials science, highlighting their potential impact.