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Nitrogen Species Modulate Macrophage ER Stress to Preserve Alveolar Bone: A Translational Adjunct for Periodontal Care | Synapse
March 3, 2026
Open Access
Nitrogen Species Modulate Macrophage ER Stress to Preserve Alveolar Bone: A Translational Adjunct for Periodontal Care
ZL
Zhixin Liu
Huazhong University of Science and Technology
LW
Laidi Wu
Huazhong University of Science and Technology
ML
Ming Luo
Huazhong University of Science and Technology
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Puntos clave
Alveolar bone preservation is significantly enhanced through nitrogen species modulation, indicating its critical role in periodontal health.
Macrophage endoplasmic reticulum stress is a central mechanism impacted by nitrogen species, affecting bone stores.
Assessment conducted using translational approaches in alveolar tissue models to investigate biological mechanisms.
These findings call for further examination of nitrogen species as potential adjuncts in periodontal treatment strategies.
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Liu et al. (Tue,) studied this question.
synapsesocial.com/papers/69a76666badf0bb9e87dcdbd
https://doi.org/https://doi.org/10.1016/j.identj.2025.109400
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