March 3, 2026Frontiers in Endocrinology1 citationsOpen Access

Association of apolipoprotein E gene polymorphisms with risk of coronary artery disease in a Han Chinese population at middle and high altitude in China

FZFanrong ZengDongguan People’s Hospital XZXinyi ZhangBeijing Tongren Hospital MZMeng ZhangDongguan People’s Hospital

Puntos clave

The APOE ε3ε4 genotype is linked with higher risk of coronary artery disease.
Individuals with this genotype show an increased likelihood of CAD onset at middle and high altitudes.
The analysis emphasizes genetic factors in coronary artery disease risk management.
Findings support the notion that genetic predisposition plays a role in CAD risk among specific populations.

Resumen

These findings validated that the APOE gene's ε3ε4 genotype is a potential predictor for CAD onset in Han Chinese individuals at middle and high altitudes.

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Cite This Study

Zeng et al. (Tue,) studied this question.

synapsesocial.com/papers/69a76681badf0bb9e87dd3e5 https://doi.org/https://doi.org/10.3389/fendo.2026.1765770

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