PEX13-knockout mice model Zellweger syndrome

Puntos clave

• Knockout mice display notable symptoms mirroring Zellweger syndrome, indicating the gene's importance.
• Evidence shows that the absence of PEX13 leads to significant peroxisome dysfunction.
• This analysis utilized a gene knockout approach to examine the role of PEX13 in cellular processes.
• Findings highlight the critical relationship between PEX13 and peroxisome-related disorders, suggesting further research in this area.